The Centennial Museum is an academic support and outreach unit of The University of Texas at El Paso focusing primarily on the natural and cultural history of the Chihuahuan Desert. It promotes and shares knowledge and understanding of the natural diversity of the region and its people. The museum meets its responsibilities through the presentation and curation of the permanent collections, including the Chihuahuan Desert Gardens. Furthermore, the museum promotes the scholarly research of UTEP students, faculty, and alumni, and supports the general mission of The University of Texas at El Paso.

The El Paso Centennial Museum was built to celebrate the anniversary of Texas independence, making it the oldest museum in El Paso. Permanent exhibits in the museum focus on the natural and cultural history of the Chihuahuan Desert region, the largest desert in North America, and the ties of friendship that exist between the University and Bhutan can be seen in its surroundings